Wild Oil Of Oregano-How And Why To Use For Gut Disorders
October 10, 2023
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Looking for a potencial way to bring your inflammation down? In this post, we will discuss all the benefits of peptides, the latest trends, and the TOP 4 Peptides that we have enjoyed using for Crohn’s & Colitis! Let us at Crohn’s & Colitis Lifestyle offer our tips on these peptides!
Before we go into the fabulous benefits of peptides here is a quick overview of peptides.
Peptides are the smallest molecule of a protein. So the breakdown goes as follows from largest to smallest: protein, amino acids, and then peptides. Peptides are made of amino acids in the body. You can think of them as amino acids, the building blocks of the structure of our body.
A peptide is made up of at least two or more amino acids. These short chains of amino acids are linked by a peptide bond which then creates structures that become proteins. But there are different kinds of peptides and proteins!
According to this resource, see the difference between peptides and proteins:
“The terms “peptide” and “protein” are commonly confused. Not all peptides form proteins, but all proteins consist of peptides. Proteins are large peptides (polypeptides) containing 50 or more amino acids or molecules that consist of multiple peptide subunits. Also, proteins typically display more complex structures than simpler peptides.
Peptides are biologically and medically important molecules. They naturally occur within organisms, plus lab-synthesized compounds are active when introduced into a body. Peptides act as structural components of cells and tissues, hormones, toxins, antibiotics, and enzymes. Examples of peptides include the hormone oxytocin, glutathione (stimulates tissue growth), melittin (honey bee venom), the pancreatic hormone insulin, and glucagon (a hyperglycemic factor).”
https://www.thoughtco.com/what-is-a-peptide-definition-examples-4177787
You can see how there are different types of peptides in the body, and they do so many things!
1) BCP-157
2) KPV
3) Thymosin Alpha-1
4) Thymosin Beta-4 (TB-500)
Here we will break down each one!
BPC-157 stands for Body Protection Compound 157. This peptide was found ironically while looking for a cure for Crohn’s disease. It is a naturally occurring peptide in human gastric juices. It being naturally occurring makes it a potentially safe and effective peptide.
BPC 157 is a peptide chain composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice found in the stomach.
Most peptides have to be used as a subcutaneous injection and BPC 157 is one of the very few that is stable enough to be used in capsule form which makes it a little bit cheaper to get and can be taken orally which many people prefer so they don’t have to get a shot.
This peptide has been clinically shown that could assist with fissures, fistulas, ulcers, and the mucosal lining of the gut, and it can even heal tissues and ligaments in the body.
We’ve found, in our own experiences that BPC it could potentially make more of an impact when the peptide can be used locally where the disease is inflamed. If a person has severe colon issues and takes it orally we found it not as effective as a person who has terminal ileum issues or ulcers on the upper GI tract. Some have noted that they use the BPC as a suppository or enema to stop bleeding, heal ulcers, reduce inflammation in the colon, and stop colon spasms which can occur with chronic diarrhea.
BPC 157 has been shown could potentially help to protect organs and helps to prevent gastric ulcers. The use of this peptide has shown pain-relieving characteristics. Those who suffer from discomfort due to muscle sprains, tears, and damage may benefit from treatment with this peptide.
It’s been estimated to be used by a few hundred thousand people with minimal to no side effects.
*NOTE: This peptide comes in capsule form as this peptide is stable enough (unlike others) to be in a capsule, so this is a big plus for people as there is no need for injections. This means that it can be taken orally or in an enema!
KPV is a naturally occurring peptide in the body and a lot of research on KPV is in the treatment of inflammatory bowel disease. They found that it might be a new and helpful therapy for IBD. According to this study (DSS-colitis model), they found taking KPV led to earlier recovery regained body weight, and reduced inflammation.
Benefits of KPV
KPV significantly decreased inflammation in colitis in this study, and this is because it decreases the inflammatory response by inhibiting proinflammatory cytokine (molecule) synthesis and secretion.
In the case of the colitis study, KPV reduced weight loss, colonic activity, and decreased inflammation and proinflammatory cytokine levels. KPV can potentially calm the response of colonic epithelial and immune cells and reduced the incidence of the study of Colitis in vivo.
KPV also can potentially support the healing of the mucosal lining of the gut. In one study KPV was given to mice with Ulcerative Colitis, in combination with other therapeutic substances. These mice experienced significant improvements in body weight, colon length, and disease symptoms.
KPV can also be a very valuable asset for its antimicrobial properties.
In addition to its anti‐inflammatory effect, KPV also has antimicrobial effects against pathogens. Its antimicrobial effects were demonstrated on two major pathogens called S. aureus and C. Albicans.
Possible colon cancer prevention therapy?
KPV tends to turn off cytokine reactions and might possibly stop inflammation, so consult your healthcare professional if this might be a strategy you can use.
We think KPV could possibly be used a long-term maintenance product for someone with Crohn’s or Colitis if their healthcare professional agrees.
Three quick benefits of KPV for the GI tract:
*NOTE: This peptide comes in capsule form as this peptide is stable enough (unlike others) to be in a capsule, so this is a big plus for people as there is no need for injections. This means that it can be taken orally or even in an enema!
Thymosin Alpha-1 is a natural regulator of immune function. It has since been studied for cystic fibrosis, infection (e.g. tuberculosis, cytomegalovirus), respiratory disorders, chronic hepatitis, and cancer. Thymosin alpha-1 was first discovered in 1972 and was isolated from tissue of the thymus gland and is a potent immune function modulator.
What is TA1?
Thymosin Alpha-1 is a major component of Thymosin Fraction 5 and is responsible for restoring and modulating immune function, particularly cell-mediated immune function. Recent studies showed that Thymosin Alpha-1 molecule increased major histocompatibility complex (MHC) class-1 and Toll-like receptor expression as well as cytokine production, suggesting its immunoregulatory role.
It is an FDA-approved medication under the trade name Zadaxin after it received orphan drug approval status. It is widely used and studied in multiple types of cancer and viral illnesses. Some physicians are using thymosin for chronic fatigue and Lyme disease as well as autoimmune function.
TA 1 is thought to modulate the immune system by augmenting T-cell function. TA1 may affect thymocytes by stimulating their differentiation or by converting them to active T cells. TA1 is rapidly absorbed, achieving peak serum concentrations within two hours.
How does Thymosin Alpha-1 work?
T-cells come in two forms: killer and helper cells. Killer T-cells are responsible for hunting down and destroying our body’s own cells that are cancerous or infected with bacteria or viruses. TA1 is thought to modulate the immune system by augmenting T-cell function. TA1 may affect thymocytes by stimulating their differentiation or by converting them to active T-cells.
Benefits based on Research and the Literature:
Thymosin Alpha-1 has been shown to:
– Exhibit antibacterial properties
– Exhibit antiviral properties
– Exhibit antifungal properties
– Increase vaccine effectiveness
– Suppress tumor growth
– Enhance function of certain immune cells
– Help eradicate unhealthy cells
– Stop infection or cancer growth
– Strengthen your immune system
– Improve symptoms associated with chronic fatigue
* Its ability to assist with immune function, its antiviral, and its antifungal properties are just a few reasons why we chose this in our top 4!
*NOTE: This peptide comes in the subcutaneous form which means it needs to be injected into the skin for administration. This peptide is not stable enough to be in a capsule or other forms of administration. Feel free to ask the company for administration tips if you have questions regarding this peptide.
TB-500 also known as Thymosin Beta 4 is a naturally occurring peptide. It is found in high concentrations in blood platelets, wound fluid, and other tissues in the body. TB-500 is not a growth factor; rather, it is a major action regulating peptide. TB-500 (Thymosin Beta 4) has been found to play an important role in the protection, regeneration, and remodeling of injured or damaged tissues. The gene for TB-500 (Thymosin Beta 4) has also been found to be one of the first to be upregulated after a wound occurs.
Thymosin beta-4 (TB4) is a 43 amino acid, 5kDa polypeptide that is an important mediator of cell proliferation, migration, and differentiation. TB4 is the most abundant member of the β- thymosin family in mammalian tissue and is regarded as the main G-actin sequestering peptide. It is found in all tissues and cell types except red blood cells. Thymosin beta-4 is angiogenic and can promote endothelial cell migration and adhesion, and angiogenesis. TB4 also accelerates wound healing and reduces inflammation and scarring when applied in dermal wound-healing assays.
Animal studies of disease and repair when using thymosin beta-4, the major actin-sequestering molecule in mammalian cells, have provided a base for the ongoing multicenter clinical trials for wound healing, including dermal, corneal, and cardiac. TB4 has multiple biological activities, which include down-regulation of inflammatory chemokines and cytokines, and promotion of cell migration, blood vessel formation, cell survival, and stem cell maturation.
Thymosin beta-4 also inhibits inflammation, microbial growth, scar formation (by reducing the level of myofibroblasts), and apoptosis, and protects cells from cytotoxic damage, including glutamate neuronal toxicity. In addition, it binds to G-actin, blocks actin polymerization, and is released with factor X by platelets. These activities contribute to the multiple wound healing properties that have been reported in animal and human studies.
Benefits of Thymosin Beta-4
– Aide in wound healing
– Improve cell responses to stress
– Help cells to live longer
– Assists with blood vessel repair
– Potential to help with ocular (eye) repair
– Known to produce a vast array of healing and regenerative effects
– Can promote bone remodeling
– Potential growth after fracture to the healing of heart muscle after a myocardial infarction (heart attack)
– May improve neurological outcomes after stroke or brain damage.
*NOTE: This peptide comes in powder form that needs to be reconstituted with Bacterostatic water and injected subcutaneously. This peptide is not stable enough to be in a capsule or other forms of administration. Feel free to ask the company for administration tips if you have questions regarding this peptide.
We are very selective in the products we recommend to our clients ensuring they are ‘gut friendly.’
We have found all of these peptides to be very beneficial and proven to target and help the gut VS. other peptides, but consult your medical professional before trying!
If you have tried any of the peptides below and want to share your experience please comment below!
See what our clients have said about all of these peptides:
In this section, we provide you with simple takeaway tips and a quick reference guide from us so that you can implement this in your daily health regimen!
*A quick tip:
Many of our members like to take their peptide of choice in the morning or at night on an empty stomach. This seems to give the body the best way of consuming this particular product.
*Please NOTE: We do not recommend taking all 3 of these peptides together! Start with one peptide and see how your body responds. Pivot to the other peptides as needed and for your desired results.
You can find all of the products mentioned in our CCLIFESTYLE shop at discounted rates with the First10 – 10$ discount code!
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*This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither CrohnsColitisLifestyle, Dane Johnson, nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter need to consult their own medical professionals.
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